What is the shelf-life of the Nourishing Night Cream? Administrator March 23, 2020 11:30 Updated Once open, Nourishing Night Cream has a shelf-life of 90 days. Unopened, the shelf-life is 30 months. Related articles What should I do if I get the Nourishing Night Cream in my eyes? Instant Tightening & Restoring Serum Comments 0 comments Please sign in to leave a comment.